E-40 came through for his first all-encompassing VladTV interview, where he spoke about his 30-year career in hip-hop. He shared stories about meeting and working with 2Pac after the late rapper shouted him out on his album, and E-40 also shared a story about his last conversation with 2Pac. Moving along, E-40 addressed his relationship with Mac Dre and denied that there was any direct beef between them. He also spoke about working with Lil Jon on the monster hits "Tell Me When to Go" and "Snap Yo Fingers." To hear more, including working with T-Pain on his first feature, hit the full interview above.